Bus stations

The easiest way to get to (or to get out of) these main transportation hubs is by subway.
Take a look to the Subway map to plan the path you need to follow to reach your destination.
If you are feeling too lazy to use public transportation you can use a taxi.

North bus station
Bus station for northern destinations: Teotihuacán, Pachuca, Querétaro, Guanajuato, San Miguel de Allende, Guadalajara, San Luis Potosí, Zacatecas and so on.
Closest subway station: Autobuses del Norte (L5-yellow)

South (Tasqueña) bus station
Bus station for southern destinations: Acapulco, Ixtapa-Zihuatanejo, Taxco, Cuernavaca, Tepoztlán.
Closest subway station: Tasqueña (L2-blue)

TAPO (San Lázaro) bus station
Transportation starting-point for trips to Puebla, Tlaxcala, Veracruz, Oaxaca, Chiapas and the Yucatán Peninsula.
Closest subway station: San Lázaro (L1-pink & LB-green/gray)

West (Observatorio) bus station
Bus station for western destinations: Toluca, Morelia, Pátzcuaro and Guadalajara.
Closest subway station: Observatorio (L1-pink)